The Mayo Clinic is hosting a clinical trial that attempts to gauge the effectiveness of orthopaedic surgery with a new model. The main advantage of the new model is the lack of opioids to relieve pain after surgery. Additionally, it will also decrease symptoms of nausea, vomiting, and constipation. Researchers will assess pain levels, opioid levels, side effects, and length of hospitalization.
This is a study where participants are assigned to two groups at random. Members of both groups will not know in which they are placed. One group will be given oxycodone, an opioid pain medication, and the other group will not. The non-opioid group will be given a placebo.
- All sexes ages 18 to 90 years old
- Patients must be willing to participate and able to provide informed consent.
- Everyone must adhere to procedures of study
- An underlying diagnosis of osteoarthritis for knee arthroplasty must be possessed
- Renal or liver disease diagnosis
- Patients who have any issues receiving a spinal anesthetic or pain catheter
- Those who have taken any narcotic medications in the 3 months prior to surgery
- Patients who are allergic to or unable to tolerate any medication used in the clinical trial
- Revision hip or knee arthroplasty
- Patients who are receiving surgery and aftercare under worker’s compensation
- Patients with diabetes
- Not able to take 325 milligrams of aspirin two times per day for deep venous thromboprophylaxis
You may participate in this clinical trial at the Mayo Clinic in Florida in Jacksonville, Florida, United States, 32224. If you have any questions or concerns, please contact Lori Chase at 312-238-7503 or at email@example.com.
This study is sponsored by the Mayo Clinic and collaborated by Ambit Biosciences Corporation and Kern Medical Center. Benjamin Wilke, MD of the Mayo Clinic will be the Principal Investigator.
Clinical TrialsView All Clinical Trials
Using a Smartphone App to Aid in Mobility Following Total Knee Arthroplasty
This clinical trial aims to decrease the costliness of traditional home care after a total knee arthroplasty (TKA).…
Return to Physical Activities After Total Knee Arthroplasty
The first goal of this study is to determine how patients who used the Journey II in their total knee arthroplasty…
Multimodal Sleep Pathway for Shoulder Arthroplasty
Since sleep deprivation can negatively affect recovery after shoulder surgery. This can be due to pain, sling…
Music Therapy Versus Control for Total Knee Arthroplasty
Music has been proven therapeutic for patients undergoing surgery. While…
The Effects of Prehabilitative Exercise on Functional Recovery Following Total Knee Arthroplasty
The Carilion Clinic is hosting a clinical trial that measures how pre-surgery exercise, known as Prehabilitation,…
Improving Rehabilitation Outcomes After Total Hip Arthroplasty
The VA Office of Research and Development and the University of Colorado, Denver are hosting a clinical trial…
TracPatch in Total Knee Arthroplasty
The Consensus TracPatch is a wearable device with an accelerometer, temperature sensor and step count to monitor…